Amanita Muscaria

Muscimol Vs. Psilocybin (Introductory Guide)

Did you know that Muscimol and Psilocybin have basically nothing in common? Understanding the differences between muscimol and psilocybin is crucial for anyone interested in the world of psychoactive mushrooms. Muscimol is primarily derived from the Amanita Muscaria mushroom, while psilocybin is found in various Psilocybe mushrooms, such as the popular Psilocybe cubensis. In this in-depth guide, we will dive into the differences between Muscimol & Psilocybin, the mushrooms that they come from, and their effects. Let's dive in:

Muscimol Vs. Psilocybin

Amanita Muscaria Vs. Psilocybe Cubensis: An Overview

Before anything else, it is critical to understand Muscimol and Psilocybin come from very different mushrooms with unique biological & chemical characteristics. Muscimol comes from the Amanita Muscaria, whereas psilocybin can be found in a wide variety of Psilocybe mushrooms around the globe. Let's dive in further to each: 

1. Amanita Muscaria Mushroom:

The Amanita Muscaria, also known as the fly agaric mushroom, is recognizable for its distinct appearance characterized by a bright red cap with white spots. Here are some key features of this mushroom:
  • Habitat: Amanita muscaria is commonly found in northern temperate regions, often associated with birch and pine trees. It is mycorrhizal meaning that it grows in symbiosis with trees or other plants
  • Chemical Composition: The primary psychoactive compound in Amanita muscaria is muscimol, but it also contains high levels of Ibotenic Acid. 
  • Psychoactive Compound: Muscimol is a psychoactive compound belonging to the class of substances known as GABAergic agents.Amanita Muscaria

2. Psilocybe Mushrooms (P. Cubensis): 

P.S. You Can Buy Psilocybe Mushroom Spores Now in 48 States!

Psilocybe mushrooms are a diverse group of fungi that contain varying levels of psychoactive compounds, with Psilocybe cubensis being one of the most widely known species. Here are some noteworthy aspects of Psilocybe mushrooms:
  • Habitat: Psilocybe mushrooms can be found in various regions worldwide, favoring subtropical and tropical environments. They grow on a variety of surfaces, but are easiest to spot in cow dung or manure. Why cow crap? Well, these shrooms are saprophytic, meaning they breakdown organic matter as a source of fuel. The Amanita, as we just learned, gets its nutrients from living trees rather than dead or decaying matter. 
  • Chemical Composition: The primary psychoactive compounds in Psilocybe mushrooms are psilocybin & psilocin.
  • Psychoactive Compound: Psilocybin is a naturally occurring compound that belongs to the class of substances known as tryptamines.

Psilocybe Mushroom

Differences in The Effects of Muscimol and Psilocybin

Now that you know the differences between Amanita Muscaria and Psilocybe mushrooms, we can dive deeper into the nuances of their psychoactive compounds, Muscimol and Psilocybin. Here's how their effects differ: 

1. Muscimol:

  • Effects: Muscimol produces sedative and psychoactive effects, often described as dream-like or dissociative. 
  • Psychological Impact: Users may experience altered perception, euphoria, relaxation, and mild hallucinations leading to increased appetite & quality sleep. It is currently under medical trials as a natural alternative for sedatives & anesthesia
  • Duration: The effects of muscimol typically last around 3 to 7 hours, but may vary depending on a myriad of other factors like weight, age, tolerance, so on and so fourth. 

2. Psilocybin: 

  • Effects: Psilocybin induces psychedelic effects that can include sensory enhancement, visual hallucinations, and introspective experiences.
  • Psychological Impact: Users may experience altered perception, enhanced creativity, spiritual insights, and a sense of interconnectedness with the world around them. It is currently under medical trials as a natural treatment for various mental illnesses like depression and anxiety. 
  • Duration: The effects of psilocybin usually last between 4 to 6 hours, but may vary greatly. 

Of course, Amanita Muscara and Psilocybe mushrooms are both "magic" in their own way. However, it is critical to understand the distinction between the two for the sake of education, safety, and general consideration for your health. Even though both Muscimol & Psilocybin cause a reaction in your brain, you must understand that the reactions are very different, and they activate completely different parts of the brain. Mistaking one for another could lead to a severe, unintended reaction. 

Disclaimer: We offer Psilocybin mushroom spores intended for microscopy and taxonomy purposes only. Images & Text provided are for informational and educational reference only and originate from cultivators and labs outside of the USA. Buying magic mushroom spores is legal in the United States. However, cultivation of magic mushrooms, which includes all psilocybin and psilocin containing mushroom species, is illegal in many countries, including the United States. Please check your local regulations to ensure that you are following the law properly.